RESEARCH ON XANTHOHUMOL
Xanthohumol is a flavonoid found in the female cones of the common hop (Humulus Lupulus L.). The scientific world has been looking at this natural compound for many years and has conducted studies on it for its antioxidant, anti-inflammatory, antifungal, neuroprotective, anti-cancer, autoimmune and weight loss promoting properties.
Research on xanthohumol is being conducted both in vitro, i.e. under laboratory conditions, and in vivo - in animals. Also human clinical trials are also increasingly emerging. Many of these studies indicate that xanthohumol may have great potential in maintaining health. Perhaps this is the 'golden mean' the world has been searching for years.
ANTI-INFLAMMATORY EFFECT AND STRENGTHENING OF THE IMMUNE SYSTEM
Inflammation is a natural process that helps our bodies fight infection and injury. However, chronic inflammation can lead to many diseases, including cancer, heart disease and autoimmune disorders.
Xanthohumol has been found to have anti-inflammatory effects by inhibiting the production of inflammatory cytokines and reducing inflammation. Xanthohumol also reduces the activation of NF-κB, a transcription factor that regulates inflammation and is often over-activated in chronic inflammatory diseases. (3)
The efficacy of xanthohumol in reducing inflammation is extremely demonstrated in the support of COVID-19 treatment. Research has proven that xanthohumol significantly improves the clinical course in critically ill patients with this disease. Perhaps here lies the solution to future epidemiological problems. (4)
There are many examples of the efficacy of this flavonoid in supporting the treatment of inflammatory conditions - one such example is osteoarthritis (5).
CANCER-FIGHTING POTENTIAL OF XANTHOHUMOL
Cancer is the leading cause of death worldwide. The development and progression of cancer is a complex process that involves various genetic and environmental factors. Studies have shown that xanthohumol can inhibit the growth of cancer cells in different types of cancer. Xanthohumol induces cancer cell death (6) and inhibits tumour formation and metastasis (7). Xanthohumol reduces inflammation, which is a key factor in cancer development and progression. Studies have shown that xanthohumol weakens the problems that are caused by cancer cells in the lymphatic barrier. This means that it helps to prevent the spread of cancer (8). Here are some examples of cancers in which xanthohumol has been used to treat:
EFFECTS OF XANTHOHUMOL ON CARDIOVASCULAR HEALTH
Xanthohumol has been shown to have cardioprotective effects by reducing oxidative stress and inflammation. In vitro and in vivo studies suggest that xanthohumol may have beneficial effects on the cardiovascular system by lowering blood pressure (22).
It may also be beneficial in regulating cholesterol levels (23). It has been found to reduce intestinal cholesterol absorption and increase faecal cholesterol excretion in animals. This could potentially lower LDL cholesterol levels and reduce the risk of cardiovascular disease.
Therapeutic effect on arterial calcification
Xanthohumol properties for brain cells
XANTHOHUMOL AS AN AID IN THE TREATMENT OF ENDOMETRIOSIS
It was also noted that xanthohumol inhibits the growth and vascularisation of developing endometriotic lesions, which many women face.
Additional analyses showed that xanthohumol treatment had no effect on the histomorphology, proliferation and vascularisation of the uterine and ovarian horns. (35)
POTENTIAL DIRECTIONS FOR FUTURE XANTHOHUMOL RESEARCH
Xanthohumol is a powerful compound that has numerous benefits for the body and mind. Its antioxidant, anti-inflammatory, anti-cancer and neuroprotective properties make it a promising candidate to aid in the treatment of many diseases.
Although more research is needed to fully understand the potential of xanthohumol, the available evidence suggests that it can be an excellent addition to any healthy diet and therapy.
Whether you're looking to boost immunity, protect your heart or improve cognitive function, xanthohumol can be a natural solution for many ailments.
WHAT FOODS CONTAIN XANTHOHUMOL?
However, Magavena, the manufacturer of „X8” SUPPLEMENT, has used a proprietary method to obtain xanthohumol of high purity and quality and has achieved a formulation that allows this flavonoid to penetrate into the body's cells. It has been specially adapted so that the body absorbs it without difficulty after direct ingestion.
WHAT AMOUNT OF XANTHOHUMOL SHOULD BE TAKEN?
All reported side effects were mild, and most were reported in both study groups were investigator-induced. Tolerability results suggest that xanthohumol does not adversely affect quality of life and none of the 30 participants taking xanthohumol chose to withdraw from the study due to side effectss. (37)
CONTRAINDICATIONS FOR THE USE OF XANTHOHUMOL
RESEARCH IS STILL ONGOING
Research on the properties of xanthohumol is still ongoing, so this article will be periodically updated.